Assay Pipeline
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We Use A Novel Technology To Detect Biomarkers With Unrivalled Specificity And Throughput
Mass Spectrometry-based Targeted Proteomics
Offers unrivalled specificity where different protein isoforms or modifications can be distinguished
More powerful than genomics since it can accurately measure the ultimate products of gene expression, proteins, which are the effectors of biological function and control the workings of all cells
Robust analytical performance is maintained across different instruments, instrument vendors and different laboratories
Unique Algorithms and Workflows
We have developed entirely unique algorithms and mass spectrometry workflows for our targeted proteomics platform
This dramatically improves our throughput compared to other targeted proteomics platforms and other protein detection technologies
Our tests are designed to simultaneously measure 50+ fully calibrated biomarkers
Measuring this many molecules enables highly specific and sensitive biomarker tests, ideally suited to:
identify and recruit a specific cohort of patients onto clinical trials
demonstrate drug efficacy across multiple aspects of disease pathology
identify patients who will respond to drugs in healthcare settings
How Mass Spectrometry Works
Mass spectrometry (MS) is an analytical technique which measures the mass-to-charge ratio (m/z) of a wide range of molecules
It is widely used in the pharmaceutical industry to quantify small molecule drug candidates and is also becoming increasingly used to quantify large biomolecules (proteins, lipids, metabolites)
Unlike other types of mass spectrometry, our triple quadrupole systems allow targeted, high throughput and highly reproducible quantification which is ideally suited for clinical applications
Triple quadrupole mass spectrometry systems also allow for the development of multiplexed assays where hundreds of analytes can be quantified in a single assay

Mass Spectrometry-based Targeted Proteomics Set-Up
